August 3, 2021

THE BENEFITS OF HEMP OIL

THE BENEFITS OF HEMP OIL NEWS

‘An entourage impact’: new clues on how low-dose CBD merchandise work

1 min read

Associate Professor Jonathon Arnold.

“The Entourage Hypothesis is that cannabis ingredients interact to produce greater effects, but there is little scientific evidence to support such a claim. Our study shows that various cannabinoids interact to change the plasma levels of the cannabinoids themselves due to what is known as the “pharmacokinetic entourage effect”.

Low-dose CBD products appear to reduce anxiety and are antispasmodic for seizures. However, it remains unclear how these products achieve these results.

The study’s lead author, Dr. Lyndsey Anderson said, “Our results suggest that CBDA may play a greater role in the effects of these low-dose CBD products than previously thought. Our own preclinical studies show that CBDA reduces anxiety and seizures. This finding provides a way for us to investigate why some cannabis extracts have pharmacological effects in humans at lower doses. “

Scientists will continue to work on how this “pharmacokinetic entourage effect” could lead to observed therapeutic results for cannabinoids in humans.

The study is published today in Scientific Reports.

Explanation

This study was funded by the Lambert Initiative for Cannabinoid Therapeutics and the Australian National Health and Medical Research Council.

About the Lambert Initiative

The Lambert Initiative for Cannabinoid Therapeutics at the University of Sydney is a national and international leader in both the science of medical cannabis and the discovery and development of cannabis-based drugs.

It was founded thanks to a philanthropic donation from Barry and Joy Lambert.