Charlotte’s Net’s CW Labs Announce New Scientific Collaboration Researching Hemp CBD Efficacy

Harvard Medical School DR. Staci Gruber, Ph.D. is a lead investigator

BOULDER, Colo., February 24, 2021 / PRNewswire / – (TSX: CWEB) (OTCQX: CWBHF) Charlottes Web Holdings, Inc. (“Charlottes Web “or the” Company “), the leader in hemp CBD wellness products, today announced a long-term scientific collaboration between McLean Hospital, a Harvard Medical School Affiliate and the Company. Funding and product support are provided by the CW Labs Division of Charlottes Web Inc.

Associate Professor of Psychiatry at Harvard Medical School Dr. Staci Gruber, Ph.D. (CNW Group / Charlottes Web Holdings, Inc.)

Two different clinical studies are being conducted by lead researcher / researcher Dr. Staci A. Gruber, Ph. D, Associate Professor of Psychiatry Harvard Medical School and director of the MIND program at McLean Hospital in Belmont, Mass. These two studies will examine the effectiveness of a specially formulated hemp-derived product that is high in CBD. The results of clinical studies are to be published in 2022. Dr. Gruber also conducts a number of other studies, including a longitudinal observational study of veterans who a Charlottes Web product.

The MIND program (Marihuana Investigations for Neuroscientific Discovery) established in 2014 by Dr. Gruber is the first of its kind and is dedicated to studying the long-term effects of cannabis and cannabinoids for medical and adult use using various clinical and cognitive tools as well as multimodal neuroimaging techniques.

“We are honored to work with Dr. Gruber. Harvard Medical School and McLean Hospital about these important clinical trials, “said Tim Orr, President of Charlottes The CW Labs division of Web. “”Charlottes Web remains committed to supporting third-party research on hemp CBD that has been studied by some of the best scientists in the country. ”

Further information on the MIND program: https://www.drstacigruber.com/

About the MIND program:
In 2014 Dr. Staci Gruber started the MIND program (Marihuana Investigations for Neuroscientific Discovery) at Mclean Hospital, a Harvard Medical School Affiliate. The MIND program is the first of its kind to address the specific effects of medical cannabis use. It is intended to support a wide range of study designs that generate ecologically valid, empirically sound data in order to close the gap between politics and science. MIND uses valid, robust research models and supports numerous projects that address the effects of medical cannabis on key variables such as cognition, brain structure and function, mood, conventional drug use, quality of life, pain, sleep and other health-related dimensions. Through longitudinal research, survey studies, and clinical studies of specially formulated cannabinoid products, MIND aims to examine the unique and synergistic effects of cannabis and its ingredients in order to determine the effectiveness of cannabinoids in certain diseases and conditions and to clarify the overall effects of cannabis on cannabinoid-based treatments physical and mental health. MIND stands ready to improve the general well-being of patients by trying to harness the therapeutic potential while minimizing the harm of cannabinoid-based treatment.

about Charlottes Web and its CW Labs division

Charlottes Web Labs (“CW Labs”) is the research and development division of Charlottes Web promoting the science of hemp-derived phytocannabinoids, terpenes, and flavonoid compounds. CW Labs is headquartered at the Hauptmann Woodward Research Institute on the campus of the University at Buffalo Jacobs School of Medicine and the Center for Integrated Global Biomedical Sciences and is part of the New York State University ((sunny) Network of 64 national and international research and medical institutions.

about Charlottes Web Holdings, Inc.

Charlottes Web Holdings, Inc., a certified B Corporation headquartered in Boulder, Coloradois the market leader in the manufacture and sale of innovative wellness products made from cannabidiol (“CBD”) made from hemp under a brand family to which it also belongs Charlottes Web ™, CBD Medic ™, CBD Clinic ™ and Harmony hemp. The company’s premium quality products start with the company’s proprietary hemp genetics, 100 percent grown in American farms and processed into whole plant hemp extracts that contain a full spectrum of naturally occurring phytocannabinoids, including CBD, CBC, CBG, terpenes, flavonoids, and others useful hemp compounds. Charlottes Web product categories include CBD oil tinctures (liquid products), CBD gums (sleep, stress, inflammation recovery), CBD capsules, CBD topical creams and lotions, and CBD pet products for dogs. Charlottes The number one CBD brand in the web USA and distributed through 22,000+ retail locations, select distributors and online through the company’s website at www.CharlottesWeb.com.

Charlottes Web was founded by the Stanley Brothers with the aim of unleashing the healing powers of plants through compassion and science and to help the planet and all who live on it. Charlottes Web is a socially and environmentally conscious company and is committed to using business as a driving force and catalyst for innovation. The company evaluates informed business decisions by considering the impact of its efforts on employees, customers, the environment and diverse communities. The rate the company pays for agricultural products reflects a fair and sustainable rate that leads to higher yields, promotes regenerative farming practices, and supports U.S. farming communities. Management is of the opinion that its socially and environmentally conscious actions have a positive effect on customers, suppliers, employees and stakeholders. Charlottes Web donates a portion of its pre-tax income to charitable organizations.

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Forward-looking information
This press release contains forward-looking statements and information within the meaning of applicable securities laws. Often, but not always, forward-looking statements and information can be identified by the use of words such as “plans,” “expected,” “not expected,” “expects,” “estimates,” “intends,” “anticipates,” or ” does not anticipate “or” believe “or variations of such words and phrases, or indicate that certain acts, events or results” may “,” could “,” would “,” could “or” will “be taken, occur or achieved . Forward-looking statements or information involve known and unknown risks, uncertainties and other factors that could cause actual results, performance or success Charlottes The Web differs materially from future results, performance, or success expressed or implied by the forward-looking statements or information contained in this press release.

Risks, uncertainties and other factors associated with forward-looking information could cause actual events, results, performance, prospects and opportunities to differ materially from those expressed or implied in such forward-looking information, including assumptions about effectiveness and results the research. the adverse effects of the COVID-19 pandemic on the company’s business; and such risks contained in Charlottes Annual web information form dated March 27, 2020 and filed with Canadian securities regulators Charlottes The issuer profiles from Web on SEDAR at www.sedar.com. Readers are cautioned that the above list of factors is not exhaustive.

SOURCE Charlottes Web Holdings, Inc.

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