A Panacea Life Sciences sign in the Chemical Research Building April 7th. (Tri Duong | The Collegian)

A year ago, Colorado State University was an alumna, founder and CEO of Panacea Life Sciences, Leslie Buttorff, gifted $ 1.5 million to the university for the creation of a cannabinoid research center.

“I had the opportunity to present our gift proposal Janice Nerger, and we had the idea of ​​setting up the Panacea Life laboratory in the chemistry research building, ”wrote Buttorff in an email The colleague.

“We have always set ourselves the goal of disrupting Big Pharma. That is why it is important to us that we continue to develop new products and ways to offer people a natural alternative to plastics and pharmaceuticals,” wrote Buttorff. “Hemp has been misunderstood for far too long, and we’re excited to help people find out what a game changer it can be for their overall health and wellbeing.”

Cannabinoids are a class of molecules derived from cannabis hemp plants that promote cannabis’ potential as a pharmaceutical treatment, particularly for pain and seizures. Buttorff wrote: “CBD is the abbreviation for cannabidiol, one of the most common of over 120 cannabinoids in the cannabis plant. “

According to the Food and Drug AdministrationEpidiolex, a treatment for two rare forms of epilepsy, was the one First FDA-approved drug containing CBD.

The Novasep machine in the Panacea research laboratoryThe Novasep machine in the Panacea research laboratory April 7th. The model used for cannabidiol research is called Hipersep. (Tri Duong | The colleague)

CBD is the active ingredient in one of the PLS products. Cannabidiol oral solutionAccording to Panacea’s website, this is just one example of a cannabinoid whose research is supported at the CSU.

“The hemp plant is known to contain over 120 different cannabinoids in a single plant, with CBD and THC being the best known,” wrote Buttorff. “There is still a lot to explore on the remaining list.”

“There are many testimonials, supportive studies, and literature that demonstrate the beneficial effects of CBD on your health, particularly how it helps safely treat chronic pain, reduce stress and anxiety, relieve insomnia, relieve insomnia, and inflammation to reduce “, wrote Buttorff.

The uses of this molecule will be extended to traumatic brain injury and PTSD treatment, according to the Panacea article.

According to their website, Panacea specializes in developing therapeutic products that contain non-psychoactive cannabinoid molecules. In contrast to THC, which according to marijuana users is responsible for the “increased” feeling of euphoria and awareness, these molecules do not cause a “high” Healthline.

The gift to the CSU supports cannabinoid research in a variety of ways.

Hunter Cuchiaro, a PhD student in CSU’s chemistry department researching cannabidiol’s relationship to other molecules, wrote in an email to The colleague“The center is a state-of-the-art analytical facility that gives CSU students and faculties access to state-of-the-art research tools to investigate issues related to cannabinoids.”

The research carried out at the center is primarily concerned with the chemistry of hemp and cannabinoids – not marijuana as a psychoactive drug.

“Cannabinoids are fraudulently used on a large scale in the marketplace by misrepresenting the levels of cannabinoid present as well as the product quality,” he said Melissa Reynolds, Associate Dean of Research at the College of Natural Sciences. “Products have been reported to contain toxins, pesticides and other undesirable ingredients. The Cannabinoid Research Center will deploy state-of-the-art tools to enable the CSU to make important discoveries in cannabinoid research that will lead to new and safer uses. “

Cuchiaro hopes that one of the outcomes of the partnership will be to raise public awareness of the potential therapeutic benefits of non-psychoactive cannabinoids.

“Public perception is always in flux, but working on the CSU can foster a better understanding and support of this emerging area,” he wrote.

This collaboration between CSU and Panacea aims to fix inconsistencies in CBD testing processes, wrote Buttorff.

Consumer safety is a top priority, wrote Buttorff. The CSU’s research will help iron out some of the inconsistencies in the hemp chain.

“For example, a hemp grower supplied us with hemp that contained pesticides,” wrote Buttorff. “This hemp is unusable and so this grower has lost a lot of money. One of the projects Panacea and CSU will be working on is the inexpensive removal of the pesticides so that this hemp can be used. ”

Hunter Cuchiaro uses a micropipette to transfer a solution from a beakerGraduate research fellow Hunter Cuchiaro uses a micropipette to transfer a solution from a beaker at the Panacea research laboratory on April 7th. (Tri Duong | The Collegian)

Cannabinoids can be applied in a variety of therapeutic contexts, which is the second aspect of Panacea’s research relationship with the CSU. Cuchiaro’s research in analytical chemistry specializes in the separation and analysis of cannabinoids and other therapeutic molecules, as well as improving the materials used to perform these separations.

“We will look at separation techniques for different cannabinoids and examine all different types of strains of the hemp plant to find out how to separate the THC,” wrote Buttorff.

Panacea will also study other molecules to create new products with a wide variety of uses, Buttorff wrote.

“The purpose of the laboratory is to advance research in the hemp / cannabinoid areas,” wrote Buttorff. “The CSU benefits from the world-class laboratory we have created, which will focus on cannabinoid testing and separation.

It is on this test and segregation that Cuchiaro’s research is focused, but there is much room for growth on the subject.

“One of the advantages of the center, housed under the umbrella of the College of Natural Sciences, is that the analytical tools are available to employees from across the academic spectrum – chemists, psychologists, biologists, and plant scientists,” wrote Cuchiaro.

According to panaceaThe research center will serve as the basis for studying cannabinoids intended to grow in a variety of areas including plant genetics, agronomy, molecular mechanisms, and clinical studies in humans and animals. They have also initiated clinical trials examining the use of therapeutic CBD in dogs and Horses.

The CSU’s relationship with Panacea has enabled the university to become a leader in cannabinoid research by providing a range of research opportunities for faculties and students, Reynolds wrote.

“We believe that Hemp, as a land grant university, offers the CSU a unique opportunity to be a national leader in integrating research, engagement and learning across the entire hemp value chain – from genetics to strain development to psychological and Consumer research, “wrote Reynolds.

Noelle Mason can be reached at news@collegian.com or on Twitter @noellemaso.